When chosen from the standard feat pool through the UI, feats that have the combination CHOOSE:NOCHOICE, MULT:YES, STACK:YES cannot be unchosen if they are taken more than once. The "Fleet" feat in Pathfinder is an easy one to check.
I don't know if it affects feats with other combinations of CHOOSE/MULT/STACK. I don't know if it affects feats obtained through other means. I don't know if it affects (other) abilities with the same combination of tags.
Committed revision 24042.